Mitochondria is the 'overlap', or one of the overlaps, between cancer and other disorders which mainstream, "organized medicine" has separated and segregated in their classifications. Most medical information / product / services consumers have come through mainstream medicine at some point, typically for their formative years and a large portion of their consumer experience.
I've covered the mitochondria aspect for fatigue and pain (often called in mainstream, and elsewhere, as the term 'caught on', 'fibromyalgia') in other topics in forums and sections of forums created for people seeking information in that regard, so please take a look through the forums or use the Search bar if you're interested in seeing that information.
This is just one link I'd hope you'd find which includes info about mitochondria and chronic illness: www.lumigrate.com/forum/chronic-illness-series-1-chronic-fatigue-syndrome), from when our second 'resident MD', Wm. Marc Spurlock, was providing content at Lumigrate.
I am reflecting back a decade, to the fall of 2006, when starting with a new MD I'd tracked down via a local compounding therapist, who was a key part of how I went from being an OT 'provider' in insurance-based, organized medicine at that time, to having Lumigrate and being the truth information provider I am today (and since 2008)(with a foundation of ethics). He'd be Lumigrate's initial/first 'resident MD' for content and collaborating at Lumigrate.com.
He gave me a flyer at his rural Colorado clinic that day we met just over a decade ago, which had information about 'the mighty mitochondria'. I liked that he was so inclined for creating education handouts of his own. I was creating education materials for my OT patients, as well. So we walked along the path until spring of 2010 -- he'd taken a turn into lasers for body sculpting, Botox, and hCG for weight loss which was contrary to our group's original agreed-upon way of providing to consumers.
In the mean time, I'd encountered Dr. Spurlock when he was on Facebook and creatively and brilliantly had figured out when about to leave Fibromyalgia and Fatigue Centers how to get an audience on Facebook and then migrate them to become known himself on his own once getting his own clinic. These 'pay to play', cutting edge MDs are often put under the 'gun' and scrutinized more carefully than if they were in the mainstream, and the upside to having punishment that entails time without patient care is it provides time, and the motivation, perhaps, to create more educational materials.
Hence, you have a great series of topics in a forum at Lumigrate that's filled with things Dr. Spurlock provided, including the one with the link that includes basics about mitochondria and fatigue / fibromyalgia.
So, in looking for information online about The Mighty Mitochondria, currently, I'm pleased to say at the no-charge YouTube resource, there's this resource as a 'primer' about this topic for those who want to learn via audio/visual: www.youtube.com/watch ...
Cellular Respiration and the Mighty Mitochondria
Amoeba Sisters ....... There are WONDERFUL comments at this link, as well. Some were saying 'thanks for helping me study for my test in school tomorrow' to this one:
this is 5 hour long lessons of content covered in about 7 minutes. I LOVE THAT she ends with saying "... and stay curious."
In our human form, we are two sisters from Texas.
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Petunia is the creator of the illustrations. She times them to the Pinky's audio to create the videos. She also creates our GIFs. She (arguably) has a better sense of humor than her sister counterpart.
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Pinky writes the scripts and records her voice. She has a degree in biology, a secondary science teaching background, and a passion for EdTech. In addition, she is a public high school classroom teacher.
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Sisters from left to right: Sarina Peterson ("Petunia") and Brianna Rapini ("Pinky") at SXSWedu March 2015.
From their terms of use -- I want to point out this is why I ask for compensation for my 1:1 or 1:due or 1:group tutoring / liaison / education guidance time (or in how to strategize to put information into action and stick with it, supporting that as we go together -- and have lasting, effective change).
"Q: May I use something you created in my presentation/course/social media?
Our terms of use allows individuals or educational organizations to share/use our creations as long as creations (1) are not being used to make a profit and (2) our name is present so that we are credited (which also helps others find us!). You don't need to contact us if both of those terms are being followed. If you are unsure or have a different kind of request involving terms of use, please contact us.
EDITING TOPIC END OF NOVEMBER 2018, with reads to date of
Today YOU!, the consumer, may still be "steeping" in mainstream completely, or completely going 'outside the box' to utilize traditional, holistic, "honest medicine" approaches. Most consumers in the United States today, and certainly those utilizing Lumigrate, are working to 'integrate' things from traditional and holistic with appropriate things from modern, Western, medicine's many offerings. (By using the word "integration", I want to clarify I am not a subscriber to the "Integrative Medicine" associations, societies, and organizations. I think they started out likely doing something sensible and manipulated it. Just wanted to clarify....
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The Lumigrate YOU! Model
I want to provide this source to you, please go to the link included immediately below this paragraph, and look all around at the information provided by Travis M. Christofferson, MS, Founder and President at Single Cause, Single Cure dot org and author of Tripping Over The Truth.
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In looking into this information provider, to present this topic at Lumigrate potentially (which I've clearly done, as I liked what I saw), I found a good overview of the book, plus more than a couple of handfulls of what appear to be uncoerced comments from readers at GoodReads. www.goodreads.com/book/show/23496164-tripping-over-the-truth
(By 'coerced', I refer to what's occurred with me in about half of the cases of books I've received from authors to consider including in what I suggest to Lumigrate YOUsers. An expectation, mandate, strong request -- depending on how controlling and pushy the author is -- to give a favorable review at a certain website where a lot of books and other products are ordered / purchased online. For the record, after my initial phase at Lumigrate, I found those authors did not pass my ethics standards for long, and I have maintained their content in the forums but without "encouragement" to utilize them beyond free reading or listening. And at this point, I do not move forward with anyone using that kind of tactic.)
A masterful synchronization of history and cutting-edge science shines new light on humanities darkest diagnosis. In the wake of the Cancer Genome Atlas project's failure to provide a legible roadmap to a cure for cancer, science writer Travis Christofferson illuminates a promising blend of old and new perspectives on the disease.
Tripping over the Truth follows the story of cancer's proposed metabolic origin from the vaunted halls of the German scientific golden age, to modern laboratories around the world. The reader is taken on a journey through time and science that results in an unlikely connecting of the dots with profound therapeutic implications.
Transporting us on a rich narrative of humanity's struggle to understand the cellular events that conspire to form malignancy, it reads like a detective novel, full of twists and cover-ups, blind-alleys and striking moments of discovery by men and women with uncommon vision, grit and fortitude.
Ultimately we arrive at a conclusion that challenges everything we thought we knew about the disease, suggesting the reason for the failed war against cancer stems from a flawed paradigm that categorizes cancer as an exclusively genetic disease.
For anyone affected by this terrifying disease, and the physicians who struggle to treat it, Tripping Over the Truth provides a fresh and hopeful perspective. It explores the new and exciting non-toxic therapies born from the emerging metabolic theory of cancer. Therapies that may one day prove to be a turning point in the struggle against our ancient enemy.
We are shown how the metabolic theory redraws the battle-map, directing researchers to approach cancer treatment from a different angle, framing it more like a gentle rehabilitation rather than all-out combat. In a sharp departure from the current "targeted" revolution occurring in cancer pharmaceuticals, the metabolic therapies highlighted have one striking feature that sets them apart -the potential to treat all types of cancer because they exploit the one weakness that is common to every cancer cell: dysfunctional metabolism.
(Bolding and more paragraph breaks added by me/Mardy)(and a little punctuation and spelling changes too, which makes it more difficult for struggling brains to comprehend.) Some of my favorite comments on this tread at Good Reads about Tripping Over the Truth:
Gydle said: I gave this book four stars because I'm impressed by the amount of research and sleuthing done by the author. I have read The Emperor of All Maladies, By Muhkerjee, a doctor, which recounts the history of our relationship with cancer. This book takes it a step deeper, exploring the research avenues that were all but choked off when everyone jumped on the genetic mutation bandwagon.
It's a "scientific paradigm" story: right now, the prevailing wisdom is that cancer is caused by a series of genetic mutations that then send the cells off on a wild spree of proliferation, angiogenesis (making their own blood supply) and eventually metastasis.
This book is an attempt to explain to the layperson current scientific attempts to resuscitate an alternate theory, first posited in the early 1900s by Nobel-winning scientist Otto Warburg, that the root cause of cancer isn't in fact genetic mutation, but a faulty energy manufacturing process stemming from damage to the mitochondria.
All cancer cells share one thing: damaged mitochondria. Taking this approach to understanding and ultimately treating cancer would involve a massive paradigm shift, and those are notoriously hard to bring about in science.
So what causes what? Does the cell's compromised energy system trigger genetic damage? Or does the genetic damage cause the mitochondrial damage? The science is still evolving, and it's a very interesting read, with lots of academic backstabbing, scientists who refuse to let go of a theory they've spent their lives and enormous amounts of money exploring, and most of all, hope that the story is not over yet and that progress can still be made in our understanding of this horrible disease.
If you're not versed in biology/chemistry lingo this might be a tough read. I also think the book could stand an extensive editing session. It's self-published, and shows it, which normally makes me abandon a book in frustration, but not this one. The information is too interesting. Hopefully the errors will be corrected in future Kindle versions.
I'm presuming this review, since it had the last part about the errors, was not solicited, although I've found massive errors in one of the first books I covered at Lumigrate.com back in 2009, which has now been re-vamped for it's second edition, I noticed when seeing it on the shelves at Natural Grocers by Vitamin Cottage, my favorite overall health products store of all time (and also started in Colorado like me and Lumigrate). (Edit in 2018 -- my opinion of that organization has changed since the time of this writing. They had long been a family held company, and due to Codex, as I understand it, being signed by the US in the fall of 2009, they had to make changes and went public with family with controlling interest.) (Nothings more reliable than change will happen, right?)
Despite the expectation by the author, I wrote an honest review and still very much recommended the book because of how I saw it being used by the people I showed it to, who were consumers.
So it's possible this review was by someone who received a free copy with an expectation of a review at Good Reads, but I've never had anyone push me to do a review anywhere but Amazon. (See all the education I try to swirl into topics for consumers to learn how to become the best consumers of information they can be?)
At any rate, it was a well written overview AND brought in The Emperor of All Maladies, which Travis refers to in the Gaia interview I overview / transcribe most of and provide to be read, below.
Beyond the series of breaker lines, below, you'll find what's at the Message From The Founder tab at the website, as I think it's crucial to show this information here as simply as possible to the Lumigrate YOUser, YOU!, so you can opt to look further into this from what you gleen at this topic.
(In order to make it more readable for tired / energy-zapped brains, I've taken the liberty here to break the paragraphs up, add a little bolding, and blockquotes so it will appear a bit different than at the source, but I'm not modifying any content, naturally.) PLEASE SEEK OUT THE SOURCE SITE AT THE LINK IF YOU'RE INTRIGUED BY WHAT YOU SEE HERE.
http://www.singlecausesinglecure.org/metabolic-theory-of-cancer/
This is what is at just one of the tabs (as the 'main course', there's even more at that tab than what I've transferred here for YOU:
Remember, figuring out wellness / illness is like layers of an onion, whether you're investigating and thinking about animal (human or otherwise), plant, fish, microscopic organisms ...... or mitochondria!
Nature intends and drives for us to thrive with wellness -- it's a matter of finding what's . This takes work, to peel and slice through to get to the root / core cause(s).
Approach it with the time and energy you would learning anything important to your present and future. 
©2012 Lumigrate Onion
Naturally, "Load Theory" or "Full Barrel Syndrome" are the models we've taught over the years to show how one goes from seemingly fine to not, and how to unweight the elevator, drain the barrel, to get back to functional wellness, if not 'ideal wellness'. 
©2012 Lumigrate Elevator
From Travis' website, Single Causes Single Cure ....... Link and explanation, above..... please go see the source site....)
Something is Very Wrong
For over 50 years researchers have been hunting down, cataloging, and developing drugs to combat the genetic mutations thought to cause cancer – with remarkably little success. Enormous amounts of time and money have been spent on cancer research yet contradictions, confusion, and frustration continue to dominate the landscape of the field.
What is The Metabolic Theory of Cancer?
Put simply, the metabolic theory states that cancer originates from damage to the cell’s capacity to generate energy with oxygen (oxidative energy production), with a concurrent increase in energy generation without oxygen.
The metabolic theory of cancer is not a new theory. It was first proposed by Nobel Prize winning German biochemist Otto Warburg in 1924. The theory was subsequently discarded when it was discovered that cancer cells had mutations to DNA, the profound new molecule Watson and Crick had just reveled to the world.
A healthy cell produces 89% of its energy using oxygen, and 11% through non-oxidative metabolism (non-oxidative metabolism is also known as “fermentation”). Oxidative energy production is far more efficient than fermentation. Almost 20 times more energy is released when glucose is completely oxidized, as opposed to when it is fermented.
Mardy's Note -- go to the source to see the images.
Healthy Mitochondria. Note the abundant looping structures inside the mitochondria (cristae), this is where all energy is produced through oxidative pathways.
Image of a mitochondria from a cancer cell. Note the almost compete absence of cristae.
Oxidative energy production takes place in a cellular organelle called the mitochondria. The mitochondria are known as the cellular “power plant.”
The metabolic theory of cancer contends that cancer begins with damage to the mitochondria. The cell is then forced to shift energy production to fermentation in order to survive.
It is telling that this one feature of cancer, damaged mitochondria and increased fermentation, is present in all cancer types. Also telling is the fact that the greater the degree of fermentation displayed by a given cancer, the more aggressive the cancer. Because a tumor cell’s mitochondria are damaged, and are therefore forced to generate energy by such an inefficient pathway, they have to consume much more glucose to remain viable.
A glance at a PET scan, which uses a radioactive labeled glucose analog to image cancer, provides stunning visual evidence of the voracious appetite tumor cells have for glucose compared to normal tissue.
PET scan showing widespread metastasis
Emerging evidence suggests that all of the hallmarks of cancer can be explained by mitochondrial damage followed by a shift to non-oxidative energy metabolism. Once the oxidative energy generating capacity of the cell is impaired, the cell undergoes a dramatic transformation; important oncogenes (cancer causing genes) are switched on, initiating the uncontrolled proliferation that is the hallmark of the disease.
Some degree of metabolic dysfunction has been shown to be present in every type of cancer, regardless of tissue of origin.
Confusion Reigns
The latest push by the NCI is called the Cancer Genome Atlas Project. Its stated mission: “To systematically explore the entire spectrum of genomic changes involved in more than 20 types of human cancer.”
The goal of this ambitious project is to once and for all, find and sequence all of the genetic mutations responsible for cancer. But so far the search for causative mutations has remained elusive – in fact, to date, the data suggests that mutations may not be involved in ways previously assumed.
The genetic mutational profile of any given cancer type looks different from person to person, rendering it impossible to claim mutations are definitely responsible for the origin of the disease. To be sure, some genes are mutated more frequently than others, but it appears that no single gene, or even any combination of genes, is absolutely necessary for the development of a tumor within a person.
And to make things even more confusing, the mutational profile is different from cell to cell within the same tumor, rendering development of drugs that target mutations next to impossible. The drug targets not only change from person to person, but even within the tumor of a single individual.
One Single Comprehensive Theory
It is well established that once a cell has an impaired ability to produce energy through oxidative pathways, the genomic instability (increased potential for DNA mutations to occur) that accompanies tumor development, inevitable follows. While the genetic mutations acquired following mitochondrial impairment unquestionably contribute to the tumor cell’s qualitative features and aggressiveness, experimental evidence is unable to unequivocally assign them as the origin of the disease.
The metabolic theory contends that mutations to DNA are of secondary consequence, or an epiphenomenon to the true cause, metabolic dysfunction. While it’s true that most of the agents known to cause cancer; chemical carcinogens, viruses, radiation, and inflammation can cause mutations to DNA, it is also true these provocative agents damage the mitochondria.
The metabolic theory of cancer states that once the mitochondria of a given cell acquire a threshold degree of damage, and the cell reverts to fermentation to obtain energy, cancer has begun.
Mardy's Note: Go to the source to see the images.
Diagram showing the progression of cancer. Once a threshold degree of mitochondrial damage occurs uncontrolled proliferation begins. The different colors depict cells with different mutational profiles within the same tumor. If a drug is developed targeting a specific mutation, the presence of sub clonal populations with different mutations will most likely render it ineffectual.
Inherited Cancer Risk fits the Metabolic Theory
Mardy's Note: Go to the source to see the images.
An electron microscope image showing the location of BRCA1 within the mitochondria.
Many of you have probably heard of BRCA1. An inherited version of BRCA1 can increase a women’s risk of developing breast cancer by up to 60%. Even though genes like BRCA1 receive a lot of press and evoke fears of the inevitability of cancer, only 5 to 7% of all cancers are attributed to the genes inherited from your mother and father – most cancers arise spontaneously.
An inherited predisposition to develop cancer has been historically cited as evidence that cancer is a genetic disease – and it certainly appears that way at first glance. However, an exhaustive look at these rare inherited mutations reveal that all of them also increase the propensity of the cell to incur mitochondrial damage – leading to impaired oxidative energy production – the hallmark of the metabolic theory.
Strong Evidence
It is certainly true that all scientific endeavors are not created equal, and some experiments provide a more profound understanding of the physical world compared to others. An elegant series of nuclear/cytoplasm transfer experiments fall into this esteemed category, and are exceptionally important in revealing important qualities of the disease. In brief, the experiments consist of transferring the nucleus (this is where the DNA resides) of a cancer cell into a healthy cell that has had its nucleus removed prior.
The newly created hybrid cell has the genetic material of a cancer cell, with all of its defects, but now has the healthy mitochondria of a normal cell. Intuitively, if the origin of cancer stems solely from mutations to DNA, the newly created hybrid cells, that still retain all of the mutations, should be tumorigenic. But they are not. They are perfectly healthy. These experiments were carefully executed, with strict controls, and were found to be very reproducible.
Experiments like these provide strong evidence that damaged mitochondria appear to be the driving force behind malignancy.
Mardy's Note: Again -- Go to the source for images.
A diagram summarizing a series of experiments conclusively determining that it is the mitochondria, and not nuclear DNA, that causes cancer.
Just getting started
The therapeutic implications of the metabolic theory of cancer are enormous. It opens up profound possibilities for new avenues of treatment. Without question the metabolic therapeutic approaches explored so far have exhibited tremendous promise.
The first and most obvious place to start is by implementing a ketogenic diet, starving the cancer cells of the glucose they so heavily rely on for survival. The preclinical results have been remarkably consistent. In virtually every experiment in which the ketogenic diet has been tested in mice, tumor growth rates have slowed dramatically.
The results of the diet stand alone, but the results get really exciting when the diet is utilized in addition to other therapies. It appears that the ketogenic diet is able to put cancer cells under significant metabolic stress allowing addition therapies, like cisplatin, radiation, and hyperbaric -oxygen to push the cells over the edge, increasing their efficacy exponentially. And this is just scratching the surface. So much remains to be done.
We don’t want to sit on our hands waiting any longer.
(As stated, above, this is from the website's tab titled 'Message from the Founder'.
Dear friends of the Single Cause Single Cure Foundation
We believe cancer research is way off track.
To be sure, hope and optimism go hand and hand with cancer advocacy and research, and rightfully so. These are the emotions that motivate us. We’ve all heard news of a possible breakthrough, or of someone beating cancer against the odds. It’s human nature to stay hopeful and be optimistic in the face of despair. But reality portrays a different image of cancer – one much less hopeful.
The statistics are a cruel reminder of the fact that we are far from winning the ‘war against cancer’ declared by President Nixon in 1971. The truth is folks, the cancer death rates today, are the same as they were in 1950. Cancer will likely soon pass heart disease as America’s leading cause of death. Many of you probably think of cancer as a disease that just affects the elderly. It’s not. Cancer is the number one killer of children and all the way up to people in their thirties.
Undeniably, meaningful progress in treating cancer has remained terribly elusive. Lifestyle changes, like a reduction in smoking rates, and earlier diagnosis, account for the vast majority of progress. New chemotherapeutic drugs account for almost nothing in terms of survival rates. In fact, one of the main therapies used to treat cancer today – radiation, has been round for 100 years. It’s hard to think of another technology that has been so stagnant.
The next generation of ‘targeted’ therapies designed to singularly target the genetic defects of the cancer cell, leaving normal cells alone — the ones you hear about on the news, or read about in the paper, the ones we are told have so much promise –have been an abysmal failure. Of the 700 targeted therapies developed to date, only one, Gleevec, has made a difference in people’s lives.
There are too many examples of oncological drugs with marginal to no benefit, like bevacizumab (Avastin, Genentech) approved for metastatic breast cancer (provides progression-free survival improvement but no increase in overall survival; estimated total cost of therapy, $90,816). No increase in overall survival for a price tag of $90,816.
This is unacceptable. There is something clearly wrong here. Critically, we think the profound lack of progress is because cancer research has for too long chased a single scientific paradigm that is increasingly showing flaws.
Our scientific convictions are what make us different from the numerous other cancer foundations. Albert Einstein once said, “the definition of insanity is doing the same think over and over again and expecting different results.” Sadly, this seems to apply to cancer research today. Rather than spending money researching genetic defects with no clinical relevance, over and over again, we think there is a better way.
We are not alone. Recent evidence implicating the importance of metabolism in cancer has not escaped the attention of some prominent researchers. DNA co-discoverer, and NCI board member, James Watson, is equally frustrated with the lack of progress, and said this recently, “More attention should be paid on the metabolism of cancer……The cancer cell should be treated as a ‘sick man’ and not a ‘superman’ by attacking cancer cells where they are metabolically vulnerable.”
Without delving too far into the science, there are two facts you should know:
- No single mutation or any combination of mutations is reliably diagnostic of any type of cancer – On the whole, the cancer mutations thought to cause cancer, seem to be almost random.
- Every cancer cell has a defective metabolism, regardless of tissue type and regardless of the mutations they possess. This is where cancer is vulnerable. This is why the cancer cell is a ‘sick man’.
Preliminary research using therapies based on exploiting the metabolic vulnerability of cancer cells has shown remarkable promise – and it has only just begun.
We feel we are posed on the precipice of a new era of progress in the understanding of cancer, and therapeutic progress. The growing body of evidence is too compelling to be ignored. We have certainly chased-down and mapped-out countless dead ends in the effort to cure cancer — but it is time to recognize and admits past failures, and move forward where the evidence dictates. Once the focus of research shifts to metabolism of the cancer cell, meaningful progress may be realized where there has been none.
Our singular mission, our unrelenting goal, is to move forward with fresh vision — removing all preconceived notions and entrenched bias — and finally change the course of this insidious disease that affects us all.
Sincerely,
Travis M. Christofferson, MS
Founder and President
In my studies about health, partly due to my father's being an autistic scientist brainiac type, and my mother being incredibly strong with sticking with things (and genetics, therefore), I'm a nice mix of their influences, both genetic and environmental. Nature and nurture. I think I'd always been familiarized to genes. My father learned about genes along the way, and focused study time on it when my mother wanted to get into breeding and selling golden retrievers in the early part of the marriage in the 1950s. They continued until I was school age and had moved to Colorado's mountains and bought an old farm which had good outbuildings for dog kenneling.
Prior to that, he started realizing something was 'wrong with him' which was perhaps genetic, and he thought maybe he shouldn't marry and have a family. Being used in the US military programs for, I now believe, mind studies to do with telepathy, he went after World War II to UCLA in California, where he got a degree in psychology he was secretive or later confusing about. On his death bed, the year of the UCLA era of his life changed and made more sense. He went on to Texas then Albuquerque, where he went into a bookstore near the campus to buy a gift for his girlfriend in Texas. My mother was on a ladder shelving books. And that was that. Here I am, here YOU are, due to that meeting nearly sixty years before Lumigrate would be available for your use.
But I've forgotten most of what I've learned about such details, either at home around the dinner table or in my occupational therapy schooling in the mid 1990s, and went to brush up about genes, because something was in the back of my mind about mitochondria DNA and the mother. What I found is very interesting -- in the early part of this new century, there were some cases reported after being studied where the father's DNA was found, in rare cases, within offspring. But mostly the DNA from the sperm don't live once in the egg from the mother. This varies from what science had found and believed (and everything was based off of) before.
So this means that it's been traced back to where all people originated, and how long ago -- and there's some debate in what I found at different sources on the Internet about that, but overall what's said that I looked at dovetails with the theories and information being presented at 'truth' places on the Internet that I've been encountering from my seeking that 'layer' in recent years, increasingly.
These 'truth movement providers' are spilling the beans on the truth of history and having us rewrite what we've been taught by The System of the corrupt cabal in the shadows, which I've termed 'The Monkeys and Their Monkey Businesses' to make it lighter and clearer to YOUsers or people I'm teaching 1:1 or 1:duo or group, and disclosing about another whole type of being more advanced than ours doing genetics work with beings on planet Earth over 100,000 years ago. In Africa, they say. Of course much disinformation is out there, too, and one has to wade through a lot of information, use discernment, and that's what I bring to Lumigrate for YOUsers.
Just a little 'seed planted' here to potentially 'raise your awareness' if you're not already aware or educated about that aspect of things. Our "junk DNA" wasn't junk, folks! And it's coming into play currently more than ever, as it's getting 'turned on' for people to 'wake up' and 'ascend', it is said. Again, might be of interest to YOU to study, or it might not. I hope it did not turn anyone 'off' by reading this little sidenote.
Because mostly, for what this topic is about, I think it's important to be provided a good site for overall information about genetics, and I liked this one:
www.genesinlife.org/genetics-101/how-does-genetics-work/main-inheritance-patterns
They have WONDERFUL graphics to present the difficult to visualize information of inheritance of genetic material and the various types. This is what is said at the very bottom of the thread at the link:
Mitochondrial
Mitochondrial inheritance, also called maternal inheritance, refers to genes in the mitochondria. Although these conditions affect both males and females, only mothers pass mitochondria on to their children.
- A father can never pass on a mitochondrial condition, because he does not pass on his mitochondrial genes.
- If a mother is affected, her children will be affected, regardless of whether they are male or female, because she always passes her mitochondrial genes to all her children.
Diabetes mellitus and deafness, a rare form of diabetes, follows the mitochondrial inheritance pattern.
- When you click on the link, this is what is provided about mitochondrial inheritance
- The mitochondrion, an organelle in the cell, contains its own genome. Mutations in these genes are responsible for several known genetic diseases. Individuals only inherit mitochondrial DNA from their mothers.
Check out Genetics Home Reference for more about genetic conditions and inheritance.
I point this out because it says, as you can see, "A father can never pass on a mitochondrial condition...." but that's contrary to what I found in a very short period of time online researching mitochondrial DNA and mothers. Here's what I found:
From New Scientist
23 August 2002
Mitochondria can be inherited from both parents
By Danny Penman
Mitochondria may not be inherited solely through the maternal line, according to new research that promises to overturn accepted biological wisdom.
If confirmed by other researchers, the findings could have huge implications for evolutionary biology and biochemistry.
Robert Sanders Williams, from Duke University Medical Center in North Carolina, says the findings are “remarkable and unanticipated. This is more than a mere curiosity. It asserts the principle that it can occur in humans. It could have significant implications for the study of human evolution and the migrations of populations,” he says.
For decades biologists have assumed that mitochondria – the cells’ power stations – are inherited solely through the maternal line.
Mitochondria in the sperm from the father were presumed to be destroyed immediately after conception, leaving behind only those from the mother. But Marianne Schwartz and John Vissing from the University Hospital Rigshospitalet in Copenhagen, have discovered that one of their patients inherited the majority of his mitochondria from his father.
“Even with very sensitive methods, paternal mitochondrial DNA has never been detected in man before,” Schwartz told Reuters. “There are many examples of family pedigrees that follow mitochondrial diseases through the maternal line.”
Little oxygen
The pair made the discovery while trying to discover why one of their patients suffered extreme fatigue during exercise. The 28-year-old man had an entirely normal heart and lungs and his muscles appeared healthy. But on closer inspection, Schwartz and Vissing discovered that his muscles absorbed very little oxygen.
This led them to examine the genetic sequence of his mitochondria. They discovered two mutations in his mitochondrial DNA – one of which was responsible for his extreme fatigue.
To try and investigate the mutations further, they also sequenced the DNA of his mother, father and uncle. To their surprise, the sequence matched those of his father and uncle.
Spontaneous mutation
Muscle biopsies showed that about 90 per cent of his mitochondria came from his father. However, the mitochondria in his blood, hair roots and fibroblasts came entirely from his mother.
The two mutations appear to have arisen spontaneously during, or shortly after, conception.
The researchers think inheritance of paternal mitochondrial DNA is probably very rare. But the findings will have implications for a number of branches of biology. Evolutionary biologists often date the divergence of species by the differences in genetic sequences in mitochondrial DNA. Even if paternal DNA is inherited very rarely, it could invalidate many of their findings. It will also have implications for scientists investigating inherited metabolic diseases.
Journal reference: New England Journal of Medicine (vol 347, p576)
www.newscientist.com/article/dn2716-mitochondria-can-be-inherited-from-both-parents/
Interestingly, NewScientist dot com, not long before providing the above article, had provided one about mitochondria DNA only via the mother ...... as if they were 'priming the pump' possible, to have this come along as a follow up. (Just a guess on my part...., and perhaps not important but it might be worth considering, as it might be a clue to this puzzle.... )
Now, back to where I encountered this information source.....
End of November, 2016 -- Special deal, it's 99 cents from now until the end of the year if you want to try that deal -- there are two other prices, $20 for three months and then $9.95 after that OR pay for a year up front and get a 20% discount .... www.gaia.com/ (And they have documentaries, movies, series .... I'm enjoying as much as I have time for, and am thoroughly enjoying it! Located out of Boulder, Colorado perhaps take a look at their marketing video about their company.)
My head spins thinking about how much money it's costing them, knowing what I paid in the upstart of Lumigrate.com when we went into videotaping and producing video for our original plan for Lumigrate.com being about people purchasing seminars such as people were paying for attending live in Grand Junction, Colorado after forming a live education group in 2007, when working and collaborating with a PhD psychologist in a mainstream, organized, medicine building where I wound down my career as an occupational therapst after almost 20 years in order to go be part of what I didn't know existed --- the Truth Movement. Just following things that were 'coming to me' from a variety of senses and directions. And here we are today. ....
With Lumigrate as my 'classroom' that's free to YOU to attend, I'm a 'teacher' essentially (that can be secured for 'tutoring 1:1') where I hope to teach consumers how to become effective consumers via their research, as well as how to implement what is learned into the daily routine, and make it LASTING.
I call it the 'credit where credit is due' portion of topics, where I tell people my process. I learned of this excellent resource via Gaia.com, which is a pay to play website, which I've opted to not do with Lumigrate and instead provide content for no subscription, no need to give an email address and get into a database -- that stuff turns some people off -- and for good reason due to the mis-use by unethical entities that are mixed in on the Internet with the ethical ones, which I believe Gaia to be.
How did I learn about Gaia (formerly Gaiam, like the yoga equipment company, that's who started the website for information long ago and recently rebranded as Gaia)? Through my research in 2013 when I got 'on the bandwagon' finally, about 'chemtrails', initially, until I learned the better word for finding better sites for valid information with less disinformation sites to sort through by using 'geoengineering'. This gets you into information about the conspiracies to keep the masses dummied down (which are not theories, they are facts, it is happening), and into an interview he took the time to have or transcribed himself related to a big group of people who have a plan going on to get the power away from those who have been in power over world-wide commerce and systems (including religion and other offshoots) and shouldn't be (in my opinion).
The information trail took me into UFOs and extra terrestrials (ETs), free energy, how our secret space program's secret space craft mobilize / propel -- it's a RABBIT HOLE that takes forEVER to get through, and down in the rabbit hole you'll sooner or later find a trail that leads to David Wilcock. While he has a lot on YouTube, and on his website, it all entices you to get a subscription at Gaiam / Gaia. And then it was a matter of time available and my being settled in terms of my overall life enough to immerse into Gaia's website's content. I'm maybe not going to keep a subscription forever, so why pay for something when you can't use it for much time every month.
It's now heading into winter in western Colorado and I have weeks on end where I don't have O'Rio Grande (the dog, you can find the topic about him on the blog tab right now, and there will be more in forums soon -- use the Search bar at Lumigrate and put O'Rio into the search bar if you're interested .... ) to care for and continue working on reversing symptoms, as his family returns for holidays typically and then that time with him is no longer part of my daily routine, leaving more time for learning and providing information at Lumigrate.com.
Gaia.com has their hosts shows well arranged and when you click on a category / show you pick from there, and then after that video is over it'll give you another one, similar to how YouTube does if you set your settings to allow that. And I LOVE IT because there's a synchronicity that comes, in my case at least, with whatever I've just talked to someone about in the last day having a video that applies to them and our conversation! And that was the case here.
So far I've focused on studying what Regina Meredith has at Gaia. So I'll suggest you go to gaia.com and find the healing matrix portion, or look at whatever guides you from what you see. It's allowing, essentially, your choice to be doing similarly to 'muscle testing' or 'witching a well', divining, etc.
My gut told me to click on the open minds area, then I explored the healing matrix area and I'm providing a comment here that I found at that area ...... just to show how the comments on these websites where the users are paying helps to sort out the valid from the invalid, trolls / shills, etc.
Has Regina considered interviewing Patrick McGean about organic sulfur? He is quite a character. He is conducting an on-going study called the cellular matrix which includes 190,000 people and growing. He says use of synthetic fertilizers has vastly reduced the amount of sulfur in plants. Sulfur is necessary for every aspect of our health. He also says there is enough organic sulfur ready to go in Hawaii to cover Fukushima to end all the radioactivity, he just needs the planes to do it. Here is a link to an interview with him on oneradionetwork: http://oneradionetwork.com/health/patrick-mcgean-oxygen-is-t.... Love Regina's shows at Gaia.com ...... it seems that every time I have a video watching session, one of the videos will have something that's right on the 'spot' of a conversation I've had that DAY! It's seeming divinely guided, which might only be the case for me because it's the right 'thing' for me at this time, and someone else would not have the same affinity I have for Gaia.
I loved this comment because I've used One Radio Network extensively starting in early 2015, for a few months "devouring" the past episodes, which I thought were easier to find on their old website. They got a totally new website in 2015, and I continued to use them as a resource, but it coincided with when I had gone over the topics in their archives that appealed to me the most. This is similar strategy for learning to how I'm now using Gaia -- even more so since Gaia is subscription and I want to get as much done with using it as I can in case I can't or won't continue, but at this point in time I think I'm going to give up something in order to afford it every month. ORN is no-charge, and makes their revenue off of product. Gaia does not advertise product and sell product, they get revenue from selling the subscriptions.
I'm going to put in a few notes from this interview, below. My process on this is that I type pretty fast and put a video on my tablet, and then type as much as I can catch going over it once. Then I come back to it refreshed later, and fill in what I can, correct -- but I don't necessarily have words spelled correctly, as I'm going by phonetics and sometimes people's pronunciation and my ability to make out what they're saying gets in the way of getting it as right as we would otherwise. SO, I ENCOURAGE YOU! -- everyone -- to consider getting a subscription, even if for a short time, and watching if this is of interest to YOU! AND/OR Travis C's book, obviously.
Theories and Treatments for Cancer with Travis Christofferson
on Open Minds with Regina Meredith
August 2016 Season 6, Episode 7
Travis is the author of Tripping Over the Truth
How he ended up 'down this rabbit hole', Regina asks at the start.
He was in graduate school in a class that lead him to a book about metabolic causes of cancer, by
Tom Seyfried, PhD.
(I'm providing another link I found and liked about Dr Seyfried's work; I find it a good adjunct and complement at this point). http://www.diagnosisdiet.com/what-causes-cancer/
Travis flew to meet Tom, they talked for six hours. The Emperor of All Maladies came out in 2012, a sweeping history of cancer, which is told with a gene-centric focus. The challenge for Travis was to write the story in his book with a historical context.
Regina makes the excellent point that people who are in fear about cancer tend to look to whomever is an authority, which often is someone in a white coat. So she was thrilled about this book -- she chuckled and said her friend Sandy who told her about it said it was a 'real page turner'.
THE BIG 3 THEORIES OF CANCER, OVERVIEWED and HISTORY
Purcible Pott (sp?) was where she had him start, who was a London surgeon. Boys who were chimney sweeps, endentured servants essentially, started getting scrotal warts and it was thought to be a venerial disease. But Dr. Pott didn't think that was right, as the boys were so young and it was across this one activity. This was the leap for tying the first thing in the external environment to causing or contributing to cancer. NCI has 300-400 known carcinogens in the environment now.
When you look back in retrospect, you can see where we made mistakes. Long ago people thought cancer was caused by excessive black bile.
Somata mutation theory has been one of the key ways to look at cancer in mainstream since the mid 1970s, or 40 years now. The genes that control the cell cycle and physical mutations.
The FDA during the Clinton administration got accused of not doing enough and FDA went the route of ratcheting back on things in their position and they focused only on tumor shrinkage, which is now, in retrospect, easily seen as having been unfortunate as a paradigm of thought. Chemotherapy was really pushed with this single cell hypothesis, the FDA was not doing oversight closely. He likens it to 'carpet bombing' the body. Then mainstream stepped back to rethink.
Cancer survival rates today -- 1:3 women will be diagnosed, 1:2 men will be; 600,000 Americans each year are dying from it at this point in time.
Death rate has not changed much since 1950, in spite of all that has transpired in cancer research and treatment.
Then David Paul Huntsman who used dyes to color the cells was discussed. Late 1800s, a guy named Fleming had made a dye that would color DNA, he called them chromasomes as a result. Cancer cells, Huntsman found, were a mess -- broken, duplicated, etc. This was the first step toward the somato mutation theory.
Chickens tumor exudate was transferred to other chickens, who'd get cancer, so this spawned the viral theory of cancer, which held on until 1976, until a series of experiments proved the somato mutation theory. A clear goal from that point was to get the genome of all the DNA in cancer was to go underway in 2006, which is massively bigger than the overall human genome project.
When you sequence genomes, it's difficult what you'll see from one person to another. So these alternative theories then stepped in.
Oto Werberg was then brought up, it was the 1920s -- the viral theory was still floating around, as well as other theories. He was a pure scientist, Nobel level, regarded as the world's top biochemist. His theory was marginalized, he was snickered at by those in corners for his theories of cancer. He stayed in Germany during the war and was Hitler's oncologist, so many scientists felt people had political ideas that discredited him as they thought he should have fled and not been acting in that capacity.
overproducing lactic acid in the presence of oxygen. By the 1950s, he figured that the respiratory function of the cell was the reason, and today we know that is mitochondria. Lactic acid is then produced as a result of the damage .
By 1974 they isolated things down to a single gene how it was causing cancer, and they found it was just a distorted gene of one we already had. When it goes awry it shouts the order to destroy the cell over and over, so to speak.
Rause's work was brought in to the discussion here, I didn't catch it on the keyboard, however,
Nobody looked back at this point. DNA was discovered in 1955 -- all eyes turned to that because this thread of life and that it was connected to cancer, you can see how everyone was taken by this theory.
The Origins of Chemotherapy
The Germans bombed a harbor where there was a ship with a lot of mustard gas. The men jumped into the water with all the mustard gas and were burned by it. The samples showed depleting the immune system, lyphoid cells. Surgery and radiation were the only treatments back then. So a crazy idea, or maybe not a crazy idea, by two doctors was to inject mustard gas into the person. Sometimes it would help short-term.
Horrible side effects. These guys were doing the best they could with what they had, with a fatal disease. This is what we still have today, essentially, with chemotherapy treatment.
These were people trying to find anything to experiment with, in the day.
Combinations of chemotherapy was then to come in via Emil Fray and Emil Frayright, who were a combination of personalities where one was bold and the other cautious, and they were viewed as crazy, they were marginalized. They were viewed as dripping poison into kids. They were bold enough to try. The parents were bold enough to try, too, Regina and Travis say. They did cure these kids of ALL, and went on to cure Hodgkins disease after that, and side effects of neurological issues, but living normal lifespans.
Then people kept pushing harder and harder for cure and they were killing people with the treatment.
Total Therapy, adding radiation, and longer chemotherapy, was brought in by another frontiersman in the file -- marginalized again. NCI wards with children throwing up, no hair, created this push-pull.
What was the turning point that made those methodologies mainstream and acceptable? Regina asks.
Nixon declared war on cancer in 1971. Standard of care works well for some cancers -- testicular, for example -- but it's used as
2.9% increase in survival is what the statistics show about chemotherapy as an adjunct.
Pete Peterson. His mentor was the discoverer of mitochondria, so he took up looking at the mitochondria in cancer as he was always interested in cancer. Warberg only suspected this in his lab. The discovery of the enzyme that's the reason was discovered in Pete's lab.
Pete was known for gritty Oklahoma work ethic, not missing a day of work in decades. Then a woman, last name Young, came along to work there, and she'd literally sleep in the lab -- was possessed with focus on the metabolism of cancer.
Young would look at the way it was like an idling car in a closed garage, you have to open the door to let the toxins out. She thought about a molecule she worked with in Washington, and started testing it in petri dishes and saw it was by far and away the best thing to work against ---- this metabolic defect is in EVERY cancer cell -- it's voraciously sucking in sugar, which is what you see in PET scans is the use of gluclose. She tested it over and over, they went through pre-clinical data with mice and rabbits. And then it became embroiled in a multi-year dustup and was sidelined for a long period of time but it's now been taken back out and is underway again.
Young got a call by the father of boy with cancer who found by his research about Young.
Young started working with him a full year after the initial contact, as they needed to get approvals, plus the father went on to attempt to get doctors to administer what Young had discovered.
No doctors in America would administer what 95% of the boy's liver was affected when He died while traveling because he caught pneuomonia. He needed time to recover. The liver was in the process of recovering, they just didn't give it enough time, they discussed.
Young's continued to work on 3BP developed for use is in the works, but she had to leave Johns Hopkins and she has had a lot of setbacks.
Doctors are so scared to deviate from Standard of Care. The Hippocratic oath is to do no harm.
Single agents don't work, synergies of combinations do -- we learned this from AIDS.
The epigenetics -- mind / body connection -- is brought in here. The tissue architecture theory is brought in. What keeps a cell living in a healthy tissue architecture, it's healthy. Negative controls are released if this is disrupted -- so it's epigenetic, not genetic. "Mutations in DNA .... effect ... not cause" is a quote from the book mentioned above, which Travis put in his book and Regina brought out.
The genomic instability and the mutations, you can see why it appears they're CAUSE, but they're EFFECT.
She brings in theory of black holes and connects it to cancer and this discussion brilliantly at this point.
Measurable markers, like blood glucose, is a factor. If you're healthier as a whole, that's provable as well.
Healthy mitochondria does not allow cancer to grow.
Ketogenic diet -- you shift away from carbs to fat and protein, and your body produces ketones to replace gluclose circulating, they have to be burned metabolically. You'll put pressure on cancer cells as you take away what the cancer cells can burn (glucose) and replace it with what they can not (ketones) . Ketone bodies will, in research, do a lot of rearrangement in cancer cells. They push the genetic expression to normalize, additionally. Inflammation markers are greatly reduced in ketosis. Edema is reduced by the ketogenic diet. The die off from radiation as side effect is lessened with a ketogenic diet.
This goes hand in hand with a starvation diet, hCG with it, which was all the rage a few years ago in particular, is mentioned by host Regina Meredith. Diabetes, all inflammatory, chronic diseases are affected.
Metabolic Therapeutics conference in Tampa is where Travis was just prior to this interview.
The ketogenic diet was first proposed for epilepsy in the 1920s and was the standard of care for a while. Is it the removal of the glocuse or the addition of the ketones, they still don't know, but it's incredibly effective for seizures. The diet got forgotten in the 1930s when pharmaceuticals came out for seizure disorder.
Jim Abrahams, Hollywood movie producer -- resurrected it because his son had a very severe case of epilepsy that was not solved with mainstream medications -- First do no Harm was the movie he made that resurrected it. This essentially free dietary therapy just keeps being forgotten about. IF ketosis is effective for such a wide swath of diseases, does this show that periodically going into ketosis was and still is what people need to have for health to occur and not go into dis-ease.
Things laden with sugars -- candys and protein bars are brought up by Regina, so we're never hungry.
They discuss how it appears the body needs to go into these periodic 'mini starvations', it's like a 'house cleaning process', it eats up the disordered mitochondria and necrotic-like tissues of the body.
10,000 years ago, agriculture came along and we had cheap carbohydrates -- the population exploded as a result, but that has given us not long life spans if we're eating via this non paleolithic way. Prior to that it was eating meat, as Regina said -- you'd share a dead buffalo for a long time prior to the agricultural revolution.
From Travis' book, Marianne's case is discussed, she had glial blastoma cancer -- cancer that grows tenacles, so in her case surgery did not get all of the cancer cells in her body. Then she went on a 600 calories a day was consumed by Mary Ann and they got a complete remission in a very short period of time with her brain cancer. She quit the diet, as she felt she was starving and weak, and for unknown reasons they did not up the calories a bit (or a moderate amount, doubling to 1,200 for instance). She then took a very controversial medication for this type of cancer and died.
Royal Rife, color therapy were all killed and are making a return in underground circles more than anything. Anyone can do these things for preventative measure.
Regina Meredith was, for spiritual reasons, a vegetarian for 20 years -- very committed to it, wrote books on it, did television shows on it and then started getting sick, she discloses to Travis and the audience, as I've seen her do on many other shows. And many others have had this same occurrence, she includes. She asks about programs that use massive amounts of juice or vegan.
I thought about 'raw' at this point, because I was just reviewing a video I've suggested at another Lumigrate forums topic about Kerri Rivera and chronic conditions (autism is her niche which then spreads out from there with 'the overlapping conditions', which naturally then has parasites as the core concept -- and in that video (with Bulletproof Radio's YouTube channel, which is a good place to get ideas but I'd further investigate any leads you get there thoroughly), she brings in the major important concept that parasites are killed sometimes by cooking so you're getting more from raw than cooked --- we all benefit from learning of the parasite angle, or I call them 'the interlopers' because what people consider a 'parasite' differs so much depending on the person's background and how much they've studied 'outside the box' essentially. Back to the Travis / Regina interview.....
Medical KD/ ketogenic diet is a measurable medical intervention -- they're going down the road of proving it pre-clinically. Will KD/ ketogenic diet cure cancers? It slows the growth of tumor cells and potentiates other treatments -- less damage, side effects from drugs, for instance.
Dr Sheck in Arizona is brought up by Travis -- once we get that data it will be helpful. When people are fighting for their lives, most people search things out.
"Standard of care" is a key concept to understand as a consumer.
It will be a documented clinical study and then the providers will have to decide -- and the old standard of care, currently the mainstream, will be marginalized.
Bone broths were used in a very prominent case of reversal as well, Regina Meredith said.
The future of cancer treatment may look like KD/ ketogenic diet, combined with 3BP, and perhaps something like hyperbaric oxygen therapy / HBOT. Combinations of therapies is the key, and nobody is disagreeing with that, he says. But there's no magic bullet. Overlapping pathways with synergy is the reason. Outstanding outcomes are being seen, there are off-label uses of drugs that are being used. It's 'brutally difficult' to find the combinations, however, he said.
As much as the average person is afraid of cancer, the average provider is afraid of litigation. Until that barrier can be broken down with grace or permission, it's a key factor, which Regina brings up.
We can take control on a preventative level. Theoretically intermittent fasting, good nutrition and not being short of certain nutrients that keep mitochondria and DNA healthy, enzyme therapies, proper supplementation, mineralization, enzyme therapies -- all play a role, they discuss. (He cited Dr. Ames at this point, again.)
This would remove a major source of fear from the human species, Regina Meridith says as she ends the episode (again, titled "Theories and Treatments for Cancer with Travis Christofferson," at Gaia.com.)
"What's Up with Your Gut? with Edward Group" is what Gaia.com provided to me next ...... also excellent!
And so it goes.....
Live and learn. Learn and live better! ~~ Mardy
__________________
Live and Learn. Learn and Live Better! is my motto. I'm Mardy Ross, and I founded Lumigrate in 2008 after a career as an occupational therapist with a background in health education and environmental research program administration. Today I function as the desk clerk for short questions people have, as well as 'concierge' services offered for those who want a thorough exploration of their health history and direction to resources likely to progress their health according to their goals. Contact Us comes to me, so please do if you have questions or comments. Lumigrate is "Lighting the Path to Health and Well-Being" for increasing numbers of people. Follow us on social networking sites such as:
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